IAA07220-50ul
50ul
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| IAA07220-100ul | 100ul |
10天
|
2376.00 | 2376.00 |
 
|
|
| IAA07220-50ul | 50ul |
10天
|
1536.00 | 1536.00 |
|
|
| IAA07220-200ul | 200ul |
10天
|
3480.00 | 3480.00 |
|
| 中文名称 | 磷酸化p21蛋白抗体 |
|---|---|
| 英文名称 | Rabbit Anti-phospho-CDKN1A/p21 (Ser130) antibody |
| 别名 | CDKN1A/p21 (phospho Ser130); CDKN1A/p21 (phospho S130); p21 (phospho Ser130); Activating Fragment 1; CAP20; Cation chloride cotransporter-interacting protein 1; CDK Interacting Protein 1; CDK-interacting protein 1; CDKI; CDKN 1; CDKN1; CDKN1A; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA 6; MDA-6; MDA6; Melanoma Differentiation Associated Protein 6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; p21CIP1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wildtype p53 Activating Fragment 1; Wildtype p53-activated fragment 1; CDN1A_HUMAN. |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse,Rat, |
| 亚型 | IgG |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human P21 around the phosphorylation site of Ser130:EG(p-S)PG |
| 细胞定位 | 细胞核细胞浆 |
| 纯化方法 | affinity purified by Protein A |
| 性状 | Liquid |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分子量 | 18kDa |
| 产品介绍 | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically. |
| 选择标记产品 | AP标记 APC标记 FITC标记 CY3标记 CY5标记 Biotin 标记 PE-CY3标记 PE-CY5标记 Alexa Fluor 350 标记 Alexa Fluor 488 标记 PE标记 HRP标记 Gold标记 CY5.5标记 CY7标记 RBITC标记 PE-CY5.5标记 PE-CY7标记 Alexa Fluor 555 标记 Alexa Fluor 594 标记 Alexa Fluor 647 标记 |
