<table > <tr> <th>中文名称</th> <td>ATP结合转运因子2抗体</td></tr> <tr> <th>英文名称</th> <td>Rabbit Anti-TAP2 antibody </td></tr> <tr> <th>别名</th> <td>ABC18; ABCB3; Peptide supply factor 2; Peptide transporter PSF2; Peptide transporter TAP2; PSF2; RING 11; TAP 2; Transporter 2 ATP binding cassette sub family B.   </td></tr> <tr> <th>抗体来源</th> <td>Rabbit</td></tr> <tr> <th>克隆类型</th> <td>Polyclonal</td></tr> <tr> <th>交叉反应</th> <td>Human,Mouse,(predicted: Rat,Dog,Pig,Cow,Horse,Rabbit,)</td></tr> <tr> <th>亚型</th> <td>IgG</td></tr> <tr> <th>免疫原</th> <td>KLH conjugated synthetic peptide derived from human TAP2:451-550/686</td></tr> <tr> <th>细胞定位</th> <td>细胞膜</td></tr> <tr> <th>纯化方法</th> <td>affinity purified by Protein A</td></tr> <tr> <th>性状</th> <td>Liquid</td></tr> <tr> <th>储存液</th> <td>0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.</td></tr> <tr> <th>浓度</th> <td>1mg/ml</td></tr> <tr> <th>产品应用</th> <td>ELISA=1:5000-10000 Flow-Cyt=1μg/Test  <br /> not yet tested in other applications.<br> optimal dilutions/concentrations should be determined by the end user.</td></tr> <tr> <th>分子量</th> <td>75kDa</td></tr> <tr> <th>产品介绍</th> <td>TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.</td></tr> <tr> <th>选择标记产品</th> <td><a href=/product/IAC335662-100ul.html>AP标记</a><br><a href=/product/IAC335663-100ul.html>APC标记</a><br><a href=/product/IAC335664-100ul.html>FITC标记</a><br><a href=/product/IAC113266-100ul.html>CY3标记</a><br><a href=/product/IAC149396-100ul.html>CY5标记</a><br><a href=/product/IAC095267-100ul.html>Biotin 标记</a><br><a href=/product/IAC239699-100ul.html>PE-CY3标记</a><br><a href=/product/IAC275766-100ul.html>PE-CY5标记</a><br><a href=/product/IAC004952-100ul.html>Alexa Fluor 350 标记</a><br><a href=/product/IAC023015-100ul.html>Alexa Fluor 488 标记</a><br><a href=/product/IAC221637-100ul.html>PE标记</a><br><a href=/product/IAC203560-100ul.html>HRP标记</a><br><a href=/product/IAC185590-100ul.html>Gold标记</a><br><a href=/product/IAC131330-100ul.html>CY5.5标记</a><br><a href=/product/IAC167459-100ul.html>CY7标记</a><br><a href=/product/IAC311950-100ul.html>RBITC标记</a><br><a href=/product/IAC257829-100ul.html>PE-CY5.5标记</a><br><a href=/product/IAC293825-100ul.html>PE-CY7标记</a><br><a href=/product/IAC041076-100ul.html>Alexa Fluor 555 标记</a><br><a href=/product/IAC067744-100ul.html>Alexa Fluor 594 标记</a><br><a href=/product/IAC077200-100ul.html>Alexa Fluor 647 标记</a></td></tr> </table>