<table > <tr> <th>中文名称</th> <td>ETV3蛋白抗体</td></tr> <tr> <th>英文名称</th> <td>Rabbit Anti-ETV3 antibody </td></tr> <tr> <th>别名</th> <td>AI414410; bA110J1.4; ETS domain transcriptional repressor PE1; ETS family transcriptional repressor; ETS translocation variant 3; ets variant 3; ets variant gene 3; ets variant gene 3, ETS family transcriptional repressor; ETV3; ETV3_HUMAN; ME PE1; METS; Mitogenic Ets transcriptional suppressor; Oncogene PE1; PE 1; PE-1; PE1.  </td></tr> <tr> <th>抗体来源</th> <td>Rabbit</td></tr> <tr> <th>克隆类型</th> <td>Polyclonal</td></tr> <tr> <th>交叉反应</th> <td>(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,)</td></tr> <tr> <th>亚型</th> <td>IgG</td></tr> <tr> <th>免疫原</th> <td>KLH conjugated synthetic peptide derived from human ETV3:65-165/512</td></tr> <tr> <th>细胞定位</th> <td> 细胞核</td></tr> <tr> <th>纯化方法</th> <td>affinity purified by Protein A</td></tr> <tr> <th>性状</th> <td>Liquid</td></tr> <tr> <th>储存液</th> <td>0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.</td></tr> <tr> <th>浓度</th> <td>1mg/ml</td></tr> <tr> <th>产品应用</th> <td>ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） <br /> not yet tested in other applications.<br> optimal dilutions/concentrations should be determined by the end user.</td></tr> <tr> <th>分子量</th> <td>57kDa</td></tr> <tr> <th>研究领域</th> <td>细胞生物, 转录调节因子, 细胞分化表观遗传学, </td></tr> <tr> <th>产品介绍</th> <td>ETV3 belongs to the ETS family of transcription factors and functions as a transcriptional repressor. ETS family members share a highly conserved DNA binding domain and play a role in growth factor pathways regulating proliferation and differentiation. PE-1 is ubiquitously expressed and localizes to the nucleus. Its expression can be induced by IL-10 via the STAT3 pathway suggesting that PE-1 contributes to the IL-10 downstream anti-inflammatory effects. During terminal cell differentiation, PE-1 plays a role in growth arrest by specifically repressing the target genes that are involved in Ras-dependent proliferation. The contributions of PE-1 to these anti-proliferative effects are heavily dependent on its interaction with Gemin3. Two PE-1 isoforms exist due to alternative splicing events.</td></tr> <tr> <th>选择标记产品</th> <td><a href=/product/IAC368078-100ul.html>AP标记</a><br><a href=/product/IAC368079-100ul.html>APC标记</a><br><a href=/product/IAC368080-100ul.html>FITC标记</a><br><a href=/product/IAC120248-100ul.html>CY3标记</a><br><a href=/product/IAC156377-100ul.html>CY5标记</a><br><a href=/product/IAC102183-100ul.html>Biotin 标记</a><br><a href=/product/IAC246680-100ul.html>PE-CY3标记</a><br><a href=/product/IAC282748-100ul.html>PE-CY5标记</a><br><a href=/product/IAC011934-100ul.html>Alexa Fluor 350 标记</a><br><a href=/product/IAC029997-100ul.html>Alexa Fluor 488 标记</a><br><a href=/product/IAC228616-100ul.html>PE标记</a><br><a href=/product/IAC210506-100ul.html>HRP标记</a><br><a href=/product/IAC192506-100ul.html>Gold标记</a><br><a href=/product/IAC138312-100ul.html>CY5.5标记</a><br><a href=/product/IAC174440-100ul.html>CY7标记</a><br><a href=/product/IAC318867-100ul.html>RBITC标记</a><br><a href=/product/IAC264716-100ul.html>PE-CY5.5标记</a><br><a href=/product/IAC300806-100ul.html>PE-CY7标记</a><br><a href=/product/IAC048057-100ul.html>Alexa Fluor 555 标记</a><br><a href=/product/IAC059272-100ul.html>Alexa Fluor 594 标记</a><br><a href=/product/IAC084182-100ul.html>Alexa Fluor 647 标记</a></td></tr> </table>