IAA04560-100ul
100ul
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| IAA04560-200ul | 200ul |
10天
|
3480.00 | 3480.00 |
 
|
|
| IAA04560-100ul | 100ul |
10天
|
2256.00 | 2256.00 |
|
|
| IAA04560-50ul | 50ul |
10天
|
1365.60 | 1365.60 |
|
| 中文名称 | ELAVL2+ELAVL4蛋白抗体 |
|---|---|
| 英文名称 | Rabbit Anti-ELAVL2 + ELAVL4 antibody |
| 别名 | ELAV like 4; ELAV like neuronal protein 1; ELAV like protein 2; ELAV like protein 4; ELAVL 2; ELAVL 4; HELN1; Hu antigen B; Hu antigen D; HUB; HUD; ELAV2_HUMAN; ELAV4_HUMAN. |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Rat,(predicted: Human,Mouse,Chicken,Dog,Cow,Horse,) |
| 亚型 | IgG |
| 免疫原 | KLH conjugated synthetic peptide derived from human ELAVL2:31-110/359 |
| 细胞定位 | 细胞核 |
| 纯化方法 | affinity purified by Protein A |
| 性状 | Liquid |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分子量 | 39+42kDa |
| 研究领域 | 细胞生物, 神经生物学, 信号转导, 表观遗传学, |
| 产品介绍 | The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation. When Elav-like proteins associate with these ARE sites this degradation is inhibited, leading to an increased stability of the corresponding transcript. Elav proteins function within the nucleus, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites. |
| 选择标记产品 | AP标记 APC标记 FITC标记 CY3标记 CY5标记 Biotin 标记 PE-CY3标记 PE-CY5标记 Alexa Fluor 350 标记 Alexa Fluor 488 标记 PE标记 HRP标记 Gold标记 CY5.5标记 CY7标记 RBITC标记 PE-CY5.5标记 PE-CY7标记 Alexa Fluor 555 标记 Alexa Fluor 594 标记 Alexa Fluor 647 标记 |
