IAA04556-100ul
100ul
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| IAA04556-200ul | 200ul |
10天
|
3480.00 | 3480.00 |
 
|
|
| IAA04556-100ul | 100ul |
10天
|
2256.00 | 2256.00 |
|
|
| IAA04556-50ul | 50ul |
10天
|
1365.60 | 1365.60 |
|
| 中文名称 | 反义导向分子RGMC抗体 |
|---|---|
| 英文名称 | Rabbit Anti-RGMC/Repulsive Guidance Molecule C antibody |
| 别名 | DL M; Haemojuvelin; HEMOCHROMATOSIS; HEMOCHROMATOSIS DUE TO DEFECT IN HEMOJUVELIN; HEMOCHROMATOSIS DUE TO DEFECT IN HEPCIDIN ANTIMICROBIAL PEPTIDE; HEMOCHROMATOSIS JUVENILE; Hemochromatosis type 2 (juvenile); Hemochromatosis type 2; Hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; HEMOCHROMATOSIS, TYPE 2A; HEMOCHROMATOSIS, TYPE 2B; Hemojuvelin; HFE 2; Hfe2; HFE2A; HJV; JH; Juvenile; MGC23953; Repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC; RGMC_HUMAN. |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,) |
| 亚型 | IgG |
| 免疫原 | KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule C:205-255/426 |
| 细胞定位 | 细胞膜 |
| 纯化方法 | affinity purified by Protein A |
| 性状 | Liquid |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分子量 | 39kDa |
| 研究领域 | 细胞生物, 发育生物学, 神经生物学, 信号转导, 干细胞, |
| 产品介绍 | The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as Hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH). |
| 选择标记产品 | AP标记 APC标记 FITC标记 CY3标记 CY5标记 Biotin 标记 PE-CY3标记 PE-CY5标记 Alexa Fluor 350 标记 Alexa Fluor 488 标记 PE标记 HRP标记 Gold标记 CY5.5标记 CY7标记 RBITC标记 PE-CY5.5标记 PE-CY7标记 Alexa Fluor 555 标记 Alexa Fluor 594 标记 Alexa Fluor 647 标记 |
