HPS2387-95
208255-51-0
默认>95%HPLC,若需其他规格请洽询
产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
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HPS2387-95 | 默认>95%HPLC,若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
|
名字 | 3,5-Difluorophenylacetyl-Ala-Phg-OMe |
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序列(三字母) | 3,5-Difluorophenylacetyl-Ala-Phg-OMe |
序列(单字母) | 3,5-Difluorophenylacetyl-A-Phg-OMe |
CAS# | 208255-51-0 |
分子式 | C₂₀H₂₀F₂N₂O₄ |
分子量 | 390.39 |
纯度 | 默认>95%HPLC,若需其他规格请洽询 |
合成方法 | Synthetic |
储存条件 | -20 ± 5 °C |
应用 | Alzheimer´s Disease |
描述 | DAPM, a cell-permeable γ-secretase inhibitor with anti-aggregation properties that dose-dependently inhibits amyloid β-protein (Aβ) secretion in 7PA2 Chinese hamster ovary (CHO) cells with an half-maximal inhibitory concentration of IC₅₀ ~ 10 nM. DAPM prevents oligomer formation by selectively blocking the Aβ dimer and trimer formation at doses that allow appreciable monomer production. |