HPS2271-95
168423-05-0
默认>95%HPLC，若需其他规格请洽询
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| HPS2271-95 | 默认>95%HPLC，若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
 
|
| 名字 | Grb2 SH2 Domain Ligand |
|---|---|
| 序列(三字母) | H-Tyr(PO₃H₂)-Val-Asn-Val-OH |
| 序列(单字母) | (p)YVNV |
| CAS# | 168423-05-0 |
| 分子式 | C₂₃H₃₆N₅O₁₀P |
| 分子量 | 573.54 |
| 纯度 | 默认>95%HPLC，若需其他规格请洽询 |
| 合成方法 | Synthetic |
| 储存条件 | -20 ± 5 °C |
| 应用 | Cancer Research|Protein-Tyrosine Kinases |
| 描述 | pYVNV corresponds to residues 317 to 320 of the oncogenic protein Shc. Similar phosphotyrosine motifs are also found in receptor tyrosine kinases and substrates of them. This peptide binds with high affinity (18 nM) to the SH2 domain of the growth factor bound-2 protein (Grb2). It is a useful inhibitor of the interaction of Grb2 with Shc, or with other Grb-2-binding proteins involved in the cell signaling cascade. |
