HPS2254-95
159439-02-8
默认>95%HPLC,若需其他规格请洽询
产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
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HPS2254-95 | 默认>95%HPLC,若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
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名字 | Ac-Tyr(PO₃H₂)-Glu-Glu-Ile-Glu-OH |
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序列(三字母) | Ac-Tyr(PO₃H₂)-Glu-Glu-Ile-Glu-OH |
序列(单字母) | Ac-(p)YEEIE |
CAS# | 159439-02-8 |
分子式 | C₃₂H₄₆N₅O₁₇P |
分子量 | 803.71 |
纯度 | 默认>95%HPLC,若需其他规格请洽询 |
合成方法 | Synthetic |
储存条件 | -20 ± 5 °C |
应用 | Growth Factors|Protein-Tyrosine Kinases |
描述 | Ac-pYEEIE showed high affinity for the pp60src SH2 domain with an IC₅₀ = 0.5 µM. Additionally it blocked binding of various SH2 domain constructs to platelet-derived growth factor kinase, i.e. Src with IC₅₀ = 1.35 µM, Abl with IC₅₀ = 15.3 and Grb2 at 100 µM by 44.25%. It did not bind to Syp (N-terminal) and PLC (C-terminal) SH2 constructs. |