HPS0355-95
147396-10-9
默认>95%HPLC，若需其他规格请洽询
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| HPS0355-95 | 默认>95%HPLC，若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
 
|
| 名字 | Endotoxin Inhibitor |
|---|---|
| 序列(三字母) | H-Lys-Thr-Lys-Cys-Lys-Phe-Leu-Lys-Lys-Cys-OH (Disulfide bond) |
| 序列(单字母) | KTKCKFLKKC |
| CAS# | 147396-10-9 |
| 分子式 | C₅₅H₉₇N₁₅O₁₂S₂ |
| 分子量 | 1224.5999999999999 |
| 纯度 | 默认>95%HPLC，若需其他规格请洽询 |
| 合成方法 | 固相合成 |
| 储存条件 | 请置于-20 ± 5 °C 且避光、干燥的环境中 |
| 应用 | Antimicrobial & Antiviral Peptides|Immunomodulating Agents |
| 描述 | The cyclic peptide KTKCKFLKKC has ben shown to form a strong complex with lipid A, the toxic component of the endotoxin lipopolysaccharide (LPS) with Ka = 0.56 · 10⁷ M⁻¹. It detoxifies LPS in vitro and prevents LPS-induced cytokine release and lethality in vivo. Furthermore, it shows neither antibiotic activity nor toxicity and might therefore be useful in the prophylaxis and treatment of LPS-mediated diseases.KTKCKFLKKC bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy. |
