HPS0077-95
150238-87-2
默认>95%HPLC，若需其他规格请洽询
| 产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| HPS0077-95 | 默认>95%HPLC，若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
 
|
| 名字 | Proadrenomedullin (1-20) (human) |
|---|---|
| 序列(三字母) | H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH₂ |
| 序列(单字母) | ARLDVASEFRKKWNKWALSR-NH₂ |
| CAS# | 150238-87-2 |
| 分子式 | C₁₁₂H₁₇₈N₃₆O₂₇ |
| 分子量 | 2460.87 |
| 纯度 | 默认>95%HPLC，若需其他规格请洽询 |
| 合成方法 | 固相合成 |
| 储存条件 | 请置于-20 ± 5 °C 且避光、干燥的环境中 |
| 应用 | Cardiovascular System & Diseases |
| 描述 | Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂-terminal 20 peptide (PAMP). The i.v. administration of PAMP produces a rapid and strong hypotensive effect in anesthetized rats. It has been suggested, that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Furthermore, it has been suggested that PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice. |
